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DIKMA

Inspire™ HILIC

Inspire™ HILIC Columns 은 HPLC 컬럼입니다. 


Features of Inspire™ HILIC Columns

• Unique selectivity and increased retention for highly polar compounds

• Increased sensitivity and lower detection limits with microbore

• Enhanced retention for hydrophilic / polar compounds

• Increased laboratory throughput and productivity

• Superior batch-to-batch reproducibility

• Suitable for the separation of hydrophilic compounds such as polar acids and bases, polar compounds, nucleosides, oligonucleotides, amino acids, peptides,

and water-soluble vitamins

HILIC is normal phase chromatography of polar and ionic compounds under RP conditions. It combines the characteristics of three methods in LC-RP, NP, and

IC. InspireTM HILIC columns retain a water-enriched layer on the surface of the silica. This water layer facilitates the transfer of polar compounds onto the stationary

phase for increased retention. Separation is achieved through the partitioning of polar solutes from the high concentration, water-miscible, organic mobile

phase into the hydrophilic surface environment. Polar solutes exhibit increased retention, and elute in the order of increasing hydrophilicity. HILIC is ideal for

separating and retaining polar compounds that may not retain on traditional RP packings. Unlike reversed-phase columns, InspireTM HILIC columns retain highly

polar compounds with only small amounts of water in the mobile phase. These more volatile mobile phases increase sensitivity with microbore applications.

About Dikma HPLC Columns

Dikma has over 20 years of R&D experience in HPLC columns. Dikma HPLC columns have been widely used by

pharmaceutical manufacturers. We offer columns of ultimate performance and maximum versatility to address the

challenges and increasing needs of today’s chromatographic laboratories.


The quality of packing material is the basis for all good chromatographic separation. Dikma is in a unique position to

control the manufacturing process from start to finish, from making the high-purity (99.999%) raw silica to applying

different bonding chemistries. Furthermore, to ensure the high performance and robustness of our columns, we

maintain tight specifications during all stages of the manufacturing process and follow rigid, audited ISO 9001

procedures to guarantee reproducible products. The end results that get delivered to you are columns that perform

at their best, and offer you highly reproducible batch-to-batch results without alteration of HPLC conditions.


Dikma silica of ultra-purity and incredible smoothness

Dikma silica is extremely pure (99.999%) and free of metals. Meticulous care is given to the quality control of surface

smoothness, particle shape uniformity, pore structure and pore consistency to ensure uniformity of particle structure

and enhanced mechanical strength. Low percentages of fines from damaged silica particles strengthen the column

bed, leading to low backpressure and enhanced column performance and lifetime.

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